John Cameron Mitchell directed, starred in and wrote, with Stephen Trask, the film Hedwig and the Angry Inch (2001), for which he won Best Director at the Sundance Festival and was nominated for a Golden Globe as Best Actor. His recent Broadway production of Hedwig garnered him Tony Awards for his performance and for Best Revival. He won an Obie Award for Hedwig Off-Broadway as well for as starring in Larry Kramer’s The Destiny of Me.

He directed Tennessee Williams’ Kingdom of Earth Off-Broadway with Cynthia Nixon and Peter Sarsgaard. He directed the films Shortbus (2006), Rabbit Hole (2010) and How to Talk to Girls at Parties (2018) both starring Nicole Kidman who was nominated for Best Actress Oscar for the former. Recent TV roles include Peacock’s Joe Vs. Karole, Hulu’s Shrill, HBO’s Girls and Vinyl, CBS’s The Good Fight, Amazon’s Mozart in the Jungle, and Sandman. 

He stars in, wrote (with Bryan Weller) and directed the musical podcast series Anthem: Homunculus featuring Cynthia Erivo, Glenn Close, Patti Lupone, Denis O’Hare, Laurie Anderson and Marion Cotillard, which is playing on Luminary podcast platform. Recent TV projects include the new series Joe Exotic with co-star Kate McKinnon for NBC/Universal.